Luteolin Powder

1. Product Introduction
Luteolin powder is primarily found in various plants as glycosides, with higher concentrations in whole-leaf green orchids, peppers, wild chrysanthemums, honeysuckle, and perilla. It exhibits antitussive and expectorant properties. Recent studies indicate that respiratory symptoms like coughing, sputum production, and wheezing are linked to chronic airway inflammation, as seen in conditions such as bronchial asthma, chronic obstructive pulmonary disease (COPD), chronic pharyngitis, and allergic rhinitis. These conditions involve localized inflammatory infiltration, which disrupts airway immune responses and increases responsiveness. Traditional treatments often rely on glucocorticoids to reduce inflammation, but their long-term use is limited due to side effects. Research demonstrates that luteolin inhibits macrophage phosphorylation, suppresses transcription factor NF-kB activity, and reduces lipopolysaccharide (LPS)-induced production of cytokines IL-6 and TNF-α.

Mechanism of Luteolin
Additional studies highlight luteolin’s ability to inhibit uric acid synthesis and promote excretion. These cytokines are critical inflammatory markers, and luteolin also enhances IFN-γ levels, reduces specific IgE, and limits eosinophil infiltration. Beyond anti-inflammatory and anti-allergic effects, luteolin demonstrates anti-PDE, anti-SARS, and anti-HIV properties by inhibiting the SARS virus’s pre-S protein activity, preventing host cell entry. It is used to manage chronic coughs caused by COPD, bronchial asthma, chronic pharyngitis, and allergic rhinitis.

2. Product Specification
For luteolin sourced from Sophora japonica (rutin), contact [email protected] for details.

3. Product Function & Application
Luteolin offers anticancer, antibacterial, anti-inflammatory, expectorant, spasmolytic, anti-allergic, and immune-enhancing effects. Clinically, it alleviates coughs, reduces inflammation, and shows therapeutic potential in:

• Anti-Inflammatory: Suppresses tumor necrosis factor (TNF) and other inflammatory cytokines.
• Anti-Allergic: Inhibits IgE-mediated histamine release from mast cells, likely via Ca²⁺ influx and protein kinase C modulation.
• Anti-Inflammatory Demyelinating Diseases: Reduces macrophage phagocytosis of myelin sheaths and reactive oxygen species (ROS) production.
• Anti-Fibrosis: Mitigates liver fibrosis and hydroxyproline expression, while improving bleomycin-induced pulmonary fibrosis histopathology.
• Anti-Hyperuricemia: Inhibits xanthine oxidase, reducing uric acid formation.
• Anti-Fertility/Hormonal Effects: Exhibits dose-dependent anti-implantation activity and enhances endometrial thickness.
• Other Benefits: Combats E. coli, poliovirus, and other pathogens; regulates immunity and lowers blood pressure.

4. Delivery & Shipping
We support FedEx/DHL/UPS, air, and sea freight.

5. Why Choose Us?
The Extract Factory, established in 2015 in Xi’an’s Hi-Tech Industrial Zone, is a leading plant extract supplier in mainland China. Our annual luteolin output is 50 tons, with scalable production to meet market demands.

We serve global clients with door-to-door delivery, even in remote regions. Supported by three processing bases, we supply 500 tons of plant extracts, 1,000 tons of fruit/vegetable extracts, and 500 tons of powdered raw materials annually. Our professional team ensures end-to-end project management and after-sales support. Certifications include ISO9001, ISO22000, HACCP, KOSHER, HALAL, and GMP.

FAQ

1. Can I get free samples?
   Yes, but shipping costs are client’s responsibility.
2. Payment terms?
   T/T, Credit Card, Western Union, PayPal, etc.
3. Quality assurance?
   A decade of experience and rigorous pre-shipment inspections guarantee quality.
4. OEM services?
   Yes, contact us with your requirements for competitive pricing and rapid sampling.

For inquiries, email [email protected].

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Samantha Harris