What Is Matrine Powder?
Matrine powder is a naturally occurring quinolizidine alkaloid derived primarily from the dried roots of Sophora flavescens Alt., a well-documented botanical species widely cultivated across China and parts of East Asia. As one of the principal bioactive alkaloids found in Sophora root, matrine belongs to a family of nitrogen-containing compounds that also includes oxymatrine, oxysophocarpine, and sophocarpine. Among these, matrine and oxymatrine are typically present in the highest concentrations, making them the most commercially significant constituents.
Beyond Sophora flavescens, matrine can also be sourced from related species such as Sophora subprostrata (commonly known as Shandougen) and the above-ground portions of Sophora alopecuroides. However, root-derived matrine powder remains the industry standard for pharmaceutical-grade and nutraceutical-grade applications due to its consistently high alkaloid content and well-characterized extraction profile.
The Extract Factory specializes in producing premium matrine powder through a controlled, multi-stage extraction and purification process designed to deliver exceptional purity, batch-to-batch consistency, and full traceability — qualities that formulation scientists, brand owners, and wholesale buyers demand.
Matrine Powder Specifications & Technical Data
The following specifications represent the standard offering available from The Extract Factory. Custom assay levels and packaging configurations are available upon request for bulk and contract manufacturing clients.
| Parameter | Detail |
|---|---|
| Product Name | Matrine Powder (Sophora Root Extract) |
| Latin Name | Sophora flavescens Alt. |
| Plant Part Used | Dried Root |
| Appearance | White to off-white crystalline powder |
| Assay (Purity) | 98% (HPLC) |
| CAS Number | 519-02-8 |
| EINECS Number | 610-750-6 |
| Molecular Formula | C₁₅H₂₄N₂O |
| Molecular Weight | 248.37 g/mol |
| Melting Point | 77 °C |
| Boiling Point | 396.7 °C |
| Solubility | Soluble in water, ethanol, and polar organic solvents; sparingly soluble in non-polar solvents |
| Storage | Cool, dry, well-ventilated area; away from direct sunlight and moisture |
Botanical Source & Raw Material Quality
The quality of any matrine powder begins at the source. The Extract Factory sources Sophora flavescens root from established cultivation regions known for consistent alkaloid profiles and minimal environmental contaminants. Raw materials undergo preliminary inspection for identity, potency, heavy metals, pesticide residues, and microbial load before entering the production workflow.
This rigorous raw material gatekeeping ensures that every batch of matrine powder produced meets the stringent specifications required by pharmaceutical intermediates, dietary supplement manufacturers, and agricultural formulation companies worldwide.
Extraction & Manufacturing Process
The production of high-purity matrine powder follows a systematically controlled sequence:
- Raw Material Preparation — Sophora roots are thoroughly cleaned and washed to remove soil, debris, and foreign matter.
- Comminution (Crushing/Grinding) — Dried roots are mechanically reduced to a fine powder to maximize surface area for efficient solvent contact.
- Solvent Extraction — Ethanol and/or other food-grade or pharmaceutical-grade organic solvents are used to selectively dissolve alkaloid compounds from the plant matrix.
- Separation & Purification — The crude extract undergoes filtration, concentration, and chromatographic or crystallization steps to isolate matrine and remove undesired co-extractives.
- Concentration & Drying — The purified fraction is concentrated under reduced pressure and dried using spray drying or vacuum drying to produce a stable, free-flowing powder.
- Quality Control Testing — Each batch is tested for assay, identity, residual solvents, heavy metals, microbial limits, and particle size before release.
- Storage & Dispatch — Finished matrine powder is stored in controlled conditions and packaged according to customer specifications.
The Extract Factory operates four independent production lines dedicated to proportional extracts and high-concentration active extracts. This infrastructure, combined with a team of experienced technical specialists and dedicated quality assurance personnel, enables reliable large-scale supply without compromising product integrity.
Physical & Chemical Characteristics
Understanding the physicochemical profile of matrine powder is essential for formulators and procurement professionals:
- Physical Form: Fine, free-flowing white to off-white powder with a characteristic bitter taste.
- Stability: Stable under normal storage conditions. Protect from excessive heat, humidity, and prolonged light exposure to maintain potency.
- pH Behavior: Matrine is a weakly basic alkaloid; aqueous solutions tend toward mildly alkaline pH.
- Compatibility: Compatible with most standard excipients used in capsule, tablet, and topical formulations. Formulation developers should verify compatibility in systems containing strong acids or oxidizing agents.
- Solubility Profile: Readily soluble in water and ethanol; this makes it suitable for both oral dosage forms and liquid agricultural preparations.
Functional Properties & Industry Applications
Antimicrobial and Anti-Inflammatory Activity
Matrine has been widely studied for its broad-spectrum antimicrobial and anti-inflammatory properties. In the nutraceutical and functional food sectors, matrine powder is incorporated into formulations targeting gastrointestinal health support. Its ability to modulate inflammatory pathways makes it a valuable active ingredient for brands developing digestive wellness and immune support products.
Natural Biopesticide & Agricultural Use
One of the most significant commercial applications of matrine powder is in sustainable agriculture. As a naturally derived alkaloid pesticide, matrine offers an effective and environmentally responsible alternative to synthetic chemical pesticides. It is used for:
- Crop protection against a range of insect pests, including aphids, mites, and certain lepidopteran larvae.
- Soil health preservation, since matrine degrades more readily than persistent synthetic alternatives.
- Organic and integrated pest management (IPM) programs, where compliance with natural input standards is essential.
For veterinary and livestock applications, matrine-based preparations serve as external treatments for skin irritation and parasitic conditions, supporting animal welfare in compliance-sensitive markets.
Traditional & Emerging Health Applications
In traditional Chinese medicine and modern phytotherapy, matrine has been used for:
- Internal support for intestinal regularity and constipation relief.
- Topical applications for skin itching and dermatological comfort.
- Supportive use in managing neurasthenia and related symptoms.
These traditional uses continue to drive demand among supplement manufacturers, herbal product companies, and pharmaceutical raw material sourcing teams.
Quality Assurance & Certifications
The Extract Factory is committed to delivering matrine powder that meets the highest international quality benchmarks. Our quality management system is supported by the following certifications and capabilities:
- ISO 9001:2015 Certified — A globally recognized quality management system ensuring consistent production standards, documented procedures, and continuous improvement.
- Halal Certified — Enabling access to Middle Eastern, Southeast Asian, and other halal-compliant markets.
- Kosher Certified — Supporting distribution to North American, European, and other kosher-observant consumer segments.
- Third-Party Testing Available — All products can be submitted to internationally accredited independent laboratories for verification of assay, purity, contaminants, and residual solvents, providing an additional layer of confidence for regulatory-sensitive buyers.
Every production batch is accompanied by a Certificate of Analysis (COA) detailing key quality parameters, ensuring full transparency for downstream manufacturers and regulatory submissions.
Packaging & Shipping Options
The Extract Factory offers flexible packaging and logistics solutions to accommodate orders of all sizes, from R&D quantities to full container loads. The table below outlines standard configurations:
| Cargo Weight | Packaging Details | Shipping Method | Estimated Lead Time |
|---|---|---|---|
| Below 5 kg | Foil bag (inner); master carton or cardboard drum (outer) | International Express (FedEx / DHL / UPS) | 7–10 days |
| 5–50 kg | Double-layer PP bag inside master carton or cardboard drum | International Express (FedEx / DHL / UPS) | 7–10 days |
| 100–200 kg | 25 kg/drum with double-layer PP bag liner inside cardboard drum | Air Shipping | 7–10 days |
| Over 500 kg | 25 kg/drum with double-layer PP bag liner inside cardboard drum | Sea Shipping | 20–45 days |
Custom packaging requirements, including private labeling, moisture-barrier liners, and nitrogen-flushed containers, can be arranged for OEM and contract manufacturing partners.
Why Choose The Extract Factory as Your Matrine Powder Supplier?
With over 15 years of dedicated experience in the plant extract industry, The Extract Factory has built a reputation for reliability, technical expertise, and customer-centric service. Here is what sets us apart for wholesale buyers, brand owners, and formulation developers:
| Advantage | Detail |
|---|---|
| Responsive Communication | Dedicated account managers; inquiries answered within 12 hours. |
| Premium Raw Material Sourcing | Only high-quality, verified Sophora flavescens roots enter our production lines. |
| Customization (OEM/ODM) | Tailored assay levels, particle sizes, and packaging formats to match your formulation needs. |
| Competitive Pricing | Factory-direct pricing with volume discounts for long-term contracts. |
| Free Samples | Pre-shipment samples available for quality evaluation before committing to bulk orders. |
| Trade Assurance | Supported by third-party trade guarantee platforms for secure transactions. |
| Fast Fulfillment | Stable inventory for standard products; mass production typically completed within 7 days. |
| Independent Verification | Optional internationally authorized third-party testing on any product batch. |
Related Natural Biopesticide Products
The Extract Factory also manufactures a complementary portfolio of plant-derived biological insecticide ingredients. These products are frequently co-sourced by agricultural formulation companies seeking integrated natural pest management solutions:
| Product | Typical Assay Range |
|---|---|
| Azadirachtin | 5–10% |
| Pyrethrin | 20% |
| Sophora Extract (General Alkaloid Blend) | 2–6% |
| Rotenone | 5–40% |
| Tea Saponin | 95% |
| Allicin | 1–10% |
| Horseradish Extract | 20% |
These materials can be combined with matrine powder to create synergistic biopesticide formulations or supplied independently for diverse agricultural applications.
Get in Touch
The Extract Factory is the trusted manufacturer behind high-purity matrine powder, produced to ISO 9001 standards with full customization capability. Whether you are a supplement brand formulating a new digestive health product, an agricultural company developing a natural pest control solution, or a distributor seeking a reliable bulk supply partner, we are ready to support your project.
For product inquiries, custom specifications, sample requests, or wholesale pricing, please contact our team directly:
Email: [email protected]
We welcome OEM partnerships and look forward to becoming your long-term matrine powder supply partner.
